erythrocyte platelet leukocyte patients in subgroups with signs of atherosclerosis of the above criteria and without obvious clinical and instrumental evidence of it, these figures were slightly higher than in diabetic patients with symptoms of atherosclerosis.It is believed that in the genesis of these changes play a role, and diabetes itself, and "layered" atherosclerosis.Our data show that changes in the composition of serum glycoprotein may play some role in the development of atherosclerosis in patients with diabetes, but is unlikely to relate to basic mechanisms of this process.

number of researchers noted an increased urinary excretion in patients with atherosclerosis xanthurenic acid (N. Orlov, 1965; N. Petrova, 1966, et al.).Experimental data indicate the possibility of the same phenomenon in animals reproduced by different methods of diabetes (Co-take, Kido, 1960).We obtained clinical and laboratory evidence that patients with diabetes and urinary excretion xanthurenic acid significantly improved (LI Geller, 3. P. Kozlov

and N. End, 1970).In these our studies in 24 healthy control group xanthurenic acid daily excretion in the urine (measured by Vilenkin) averaged 6.5 ± 0.6 mg and 79 patients with diabetes - 7,9 ± 4 mg.The uniformity of changes in allocation xanthurenic acid excretion in atherosclerosis and diabetes deserves some attention in a comprehensive analysis of the ways the onset and progression of atherosclerosis in patients with diabetes.

lot of work shows the influence of serotonin on the heart and blood vessels (an overview in this area result in VV Menshikov and LS Bassalyk, 1963; V. Panchenko and TM Kalishevskaya, 1968, and others.)However, the hypothesis that serotonin is giperglikemiziruyuschim factor secreted into the bloodstream pancreaticoduodenal zone under the influence of growth hormone (Sirek e. a., 1966).

Tags: atherosclerosis, diabetes, serotonin, serum